This episode tackles the basic problem that confronts those who are overweight; how to lose weight and keep it off over the long term. In a FRONTIERS sponsored experiment, the cameras follow a dozen subjects for several months as they adopt different strategies for weight loss, ranging from...

If you lose a doctor you lose a hospital. If you lose a teacher you lose a school. If you lose a mother you lose a family.

Hollywood Hotline: Lauren Conrad's line dropped from Kitson; Megan Fox has been told to gain weight while Kim Kardashian's boyfriend wants her to lose it. And Britney's back on the scene with the 'eye of the tiger.'

Can a VC maven help you lose weight? Heidi Roizen is betting she can with SkinnySongs.com, an album of songs about weight loss that aren't corny, and a website that works outside of the music industry.

Meet African inventor who invented suit that helps you lose weight.

Lose weight fast with this amazing new diet plan!

lose weight fast with this amazing new diet plan!

Lose weight fast with this amazing new diet plan!

JOHN CREAMER & STEPHANE K WITH NADIA ALI SOMETHING TO LOSE LYRICS My heels are high and Im thinking about taking a walk Im thinking here is only dragging me down Im not afraid, Im gonna take you on Get a taste of your medicine now Cause this place Is so cold I cant stay Under your hold....

Guest stars Connie Stevens, Christopher MacDonald, Geoffrey Lewis, and Larry King. Kirstie's crack head brother arrives and suggests that Kirstie start doing crack in order to lose weight. Kirstie's dysfunctional parents try to intervene.